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KMID : 0374920040250010101
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Inje Medical Journal
2004 Volume.25 No. 1 p.101 ~ p.109
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A case of histiocytic necrotizing lymphadenitis associated with systemic lupus erythematosus
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Kim Ae-Ran
Kim Dong-Kie
Kwon Min-Jung
Park Ji-Hun
Kim Ki-Hyang
Jung Eun-Wook
Bae Kyoung-Im
Kim Yang-Wook
Kim Yeong-Hoon
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Abstract
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Histiocytic necrotizing lymphadenitis is an rare, idiopathic, self-limited inflammatory disease characterized by cervical lymphadenopathy with or without fever that presents in young women commonly. It is a distinct clinicopathologic entity with characteristic histopathologic features of necrotizing lymphadenitis. Extranodal involvement in histiocytic necrotizing lymphadenitis is rare and has been documented in the skin, bone marrow, and myocardium. Laboratory examinations show normal or nonspecific results. The disease is of unknown origin although a viral origin has been suggested. Although the first and most of the more recent cases have been reported in Oriental patients, the disease has a wide geographic distribution. The clinical evolution is favorable, with spontaneous remission in less than 4 months in almost all cases.
Histiocytic necrotizing lymphadenitis has rarely been reported associated to SLE.
We describe here a rare case of necrotizing lymphadenopathy with distinctive characteristics of primary Kikuchi disease in a patient by clinical, immunological and pathologic method diagnosed as systemic lupus erythematosus(SLE).
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KEYWORD
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Histiocytic necrotizing lymphadenitis, systemic lupus erythematosus
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